A study of the structural and functional difference in the brains of persons with bipolar disorder

If there are any in this series of five chapters you might wish to skip, this would probably be it. The others lead more directly to implications for treatment.

A study of the structural and functional difference in the brains of persons with bipolar disorder

Brain Imaging and Behavior; Apr The default mode network DMN is abnormal in a multitude of neurological and psychiatric disorders.

Inclusion criteria were peacetime or wartime veterans regardless of branch of service and included those for whom the traumatic brain injury was not service related.

A study of the structural and functional difference in the brains of persons with bipolar disorder

SPECT imaging was performed on this group both at rest and during a concentration task. These measures, as well as the baseline-concentration difference, were then inputted from DMN regions into separate binary logistic regression models controlling for age, gender, race, clinic site, co-morbid psychiatric diseases, TBI severity, whether or not the TBI was service related, and branch of armed service.

Predicted probabilities were then inputted into a receiver operating characteristic analysis to compute sensitivity, specificity, and accuracy.

The purpose of this study was to conduct an investigation of brain areas related to anxiety using SPECT scans.

Participants were administered a SPECT scan as part of a general evaluation for a wide variety of psychiatric disorders ranging from ADHD to schizophrenia and brain disorders.

They were grouped based on their responses to symptom questionnaires targeting anxiety symptoms specifically. Three groups were formed and were based on quartiles: Individuals in the moderate and high groups had significantly greater blood flow than the low group in the left cerebellum and caudate.

Individuals in the high group had significantly greater blood flow than the low group in the right cerebellum, and left and right olfactory bulbs. Individuals in the low group had greater blood flow than the high group in the left and right occipital lobe. The results demonstrated that various areas of the brain, based on average amount of blood flow, differ based on varying levels of self-reported anxiety symptoms.

No significant pattern of results emerged, which could demonstrate that blood flow in individuals with high levels of anxiety more global changes rather than specific to one area of the brain. Future research should investigate more specifically the areas of the brain that differ between individuals to determine possible mechanisms by which they influence each other.

Using a symptom checklist, participants Subjects in the upper quartile yielded significantly lower blood flow relative to the lower quartile in the following areas: The purpose of this study was to assess the differences of blood perfusion in those who scored in the upper compared to the lower quartiles of mania symptomology.

Analyses denoted significant differences in blood perfusion of those with a range of mania symptom severity.

Specifically, self-reported mania symptomology appears to be indicative of lower levels of blood perfusion in subcortical regions.

Bipolar Disorders and Depression - Chicago Psychiatry Associates

These results indicated that SPECT analysis could potentially be useful in the neurological aspect of research on mania symptomology. Ensuing research will aim to distinguish the relationship between brain areas and their associated specific symptoms.

Archives of Clinical Neuropsychology, 29 6: Data were collected from the self-reports of clients seen at the Amen Clinic. Participants included individuals with a self-reported diagnosis of an eating disorder, with an average age of The sample was mostly female, and subtypes of eating disorders were not identified.

Independent t-tests were used to analyze mean differences in blood flow between normals and eating disorders. No other areas of the brain revealed differences in blood flow while performing the CPT.

Individuals with eating disorders showed more blood flow to the right inferior orbitofrontal cortex and cerebellum during the performance of the CPT. Increased blood flow to the right inferior orbitofrontal cortex during the CPT may suggest that individuals with eating disorders may attend more to decision-making in relation to all visual stimuli, not just food and other body-related visual stimuli.

Catatonic disorders - causes, DSM, functioning, effects, therapy, drug, person, people

Increased blood flow to the cerebellum may suggest that individuals with eating disorders have increased motor control and attention. To determine which areas of the brain were most associated with level of aggression as measured via SPECT scans.

Participants were selected based on their scores on an aggression factor from a symptom checklist, and had a mean age of Digitally derived blood flow measures from areas throughout the brain were examined at activation.

Those scoring in the upper quartile of the aggression factor yielded significantly lower blood flow than those in the lower quartile in the following areas: Analyses revealed higher levels of self-reported aggression differed significantly in terms of perfusion to various areas relative to lower levels of aggression.

These findings suggest many areas mediate symptoms of aggression and that SPECT scans may be a fruitful tool in identifying those susceptible to high levels of aggression.

A study of the structural and functional difference in the brains of persons with bipolar disorder

Future research will try to differentiate which areas show the greatest contribution to aggressiveness. The study examined whether nicotine disorders affect cerebral blood flow at baseline and while concentrating.We conducted a PET imaging study at two different sites (London and Stockholm) to measure GABA A receptor availability in the brains of adults with ASD compared to adults without ASD.

We also conducted an autoradiography study in three mouse models of ASD. [The difference of fractional amplitude of low frequency fluctuation between first-episode and recurrent depressed patients: a resting-state functional magnetic resonance imaging study] Lin Chuang Jing Shen Yi Xue Za Zhi.

A study of subjects with features of schizotypy (but not clinical schizotypal personality disorder) indicated a prefrontal volume deficit (involving a region and subject pool not evaluated by our group), suggesting that there may be an abnormality of the frontotemporal connection and/or that abnormalities in schizotypal personality disorder may.

Study PSY Exam 2 flashcards from Arianna R. on StudyBlue.

Types and causes of mental disorders

- according to this perspective, persons feel depressed because they engage in depressed ways of thinking - on average, people with Bipolar I disorder experience about four recurrences in 10 years.

d Subjects: BD = bipolar disorder.4 yr) glucose uptake in right midcingulate and superior frontal gyri correlated negatively with executive functions. compared with patients (mean 30 yr) without a history of suicidal behaviour. next to possibly not the best to assess .

Relationship between suicidality and impulsivity in bipolar I disorder: a diffusion tensor imaging study. Milanovic SM, et al. An fMRI study of working memory in persons with bipolar disorder or at genetic risk for bipolar disorder.

Bijttebier S, Godfrin K. Suicidal brains: a .

structural and functional brain connectivity - pfmlures.com Transgender is the wrong word for the condition. Transgender humans were never meant to be able to actually change their body.
Archive for the ‘Bipolar Disorders and Depression’ Category Bipolar disorder is a recurrent illness with high morbidity for some patients.
Fastest Nurse Insight Engine Self-perception of being unique, superior, and associated with high-status people and institutions Needing continual admiration from others Sense of entitlement to special treatment and to obedience from others Exploitative of others to achieve personal gain Unwilling to empathize with the feelings, wishes, and needs of other people Intensely envious of others, and the belief that others are equally envious of them Pompous and arrogant demeanor Narcissistic personality disorder usually develops in adolescence or early adulthood. The NPD symptoms must be sufficiently severe that they significantly impair the person's capabilities to develop meaningful human relationships.
Flashcard Deck Information This article has been cited by other articles in PMC. Abstract Polysialic acid polySiaa unique acidic glycan modifying neural cell adhesion molecule NCAMis known to regulate embryonic neural development and adult brain functions.
Bipolar Disorder Neuroanatomy -- pfmlures.com